O i matou o se tasi o taitain-methylbenzamide fa'atau oloama tagata gaosi oloa i Saina, pe a e manaʻo e suʻefalegaosimea n-methylbenzamide, lagona le saoloto e faʻafesoʻotaʻi i matou ma lafo mai ia i matou se imeli.
1. O le aN-Methylbenzamide?
N-methylbenzamide o se phosphodiesterase 10A (pde10a) faʻamalosi lelei.O le N-methylbenzamide o lo'o iai le gaioiga fa'ama'i.Faʻavae i luga o lenei tulaga tulaga ese, suʻesuʻega ua taulaʻi tele i le faʻaogaina o le PDE10A modulators e avea o se auala faʻafomaʻi fou mo le faʻaleagaina i le basal ganglia circuit e aofia ai le maʻi o Parkinson, faʻamaʻi o Huntington, schizophrenia, vaisu ma le faʻalavelave faʻalavelave.O taumafaiga tau kemisi faʻafomaʻi na faʻaalia ai le N-methyl-N-[4-(quinolin-2-ylmethoxy) -phenyl] -isonicotinamide e avea o se inhibitor nanomolar PDE10A.O se polokalame o le Lead-optimization mulimuli ane na faailoa mai ai N-methylanilides tutusa ma a latou N-methylbenzamide tutusa e avea ma iniseti malosi PDE10A, faatasi ai ma nisi o auala manaia ma le le'i faamoemoeina na faailoaina.
76-78 ° C
167 ° C
Malosi 1.1031
Fa'asinomaga fa'afoliga 1.5589
Tulaga teuina fa'amaufa'ailoga mago, potu vevela
Soluble ethanol: soluble 50mg/ml, vai soluble: Le solu i le Vai
CAS:613-93-4
Fa'aaliga: Pa'epa'e Crystalline
2. Fa'aoga autu
Inhibitor, antikanesi, organic synthesis intermediate, fale suesue vailaʻau
3.Teuina ma le faʻapipiʻiina
3. Faiga fesoasoani muamua
Fe'ai Mata: Fufulu vave i le tele o vai, fa'apea fo'i i lalo o laumata, mo le itiiti ifo i le 15 minute.Va'ai foma'i.
Fe'ai ile Pa'u: Fufulu vave ile fasimoli ma le tele o vai a'o aveese uma lavalava ma seevae ua pisia.
Inhalation: Aveese mai le faʻaalia, taoto i lalo.Aveese i le ea fou.Afai e le manava, fai le manava faafoliga.
Fa'ai: Fa'amama gutu ile vai.Va'ai foma'i.
Fa'ailoga sili ona taua ma a'afiaga: Leai se fa'amatalaga e maua.
Puipuia o le Tagata Lava i le Fesoasoani Muamua: Leai se puipuiga faʻapitoa e manaʻomia.
Fa'amatalaga mo Foma'i: Togafiti fa'ailoga.
4. Fa'amatalaga felauaiga
Femalagaiga i Auala ma Alatele : E le fa'atulafonoina
IMDG/IMO : E le fa'atulafonoina
IATA : E le fa'atulafonoina
Lapataiga Fa'apitoa mo Tagata Fa'aoga: Leai se puipuiga fa'apitoa e mana'omia
5. alaleo HTML5
Hebei Guanlang Biotechnology Co., Ltd. o le Guanlang Group, lea na faavaeina i le 2007, o loʻo i Shijiazhuang aai o le laumua o le Itumalo o Hebei ma le vaega hub i totonu o Beijing Tianjin ma Hebei ma maua ai le avanoa o felauaiga talafeagai.O la matou kamupani o se pisinisi fa'aonaponei fa'aonaponei fa'aonaponei fa'aonaponei ma Su'esu'ega & Atina'e, gaosiga ma le fa'atauga. E iai a matou fale gaosimea ma fale su'esu'e, e ofoina atu fo'i auaunaga fa'apitoa mo a matou tagata fa'atau.
